This 24-place centrifuge has been engineered to be extremely quiet. Short runs up to 12 minutes are whisper quiet at an average of 45 dB(A). This is sufficient for centrifugation steps of most routinely used DNA/RNA purification kits. During longer runs the cooling fan works at full capacity to dissipate the heat for the remainder of the run. Centrifuge 5425 is the successor of the legendary Centrifuge 5424. It has everything you loved before plus great new features to make everyday work more enjoyable.