HPPCeco-AMI: Automated Microscopy for Climate-Controlled Investigations

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HPPCeco-AMI: Automated Microscopy for Climate-Controlled Investigations

For researchers working with temperature and humidity sensitive samples, the challenge of microscopic imaging within a controlled environment is a familiar one. Extracting samples disrupts the meticulously maintained conditions, potentially compromising the integrity of your experiment.  Memmert's HPPCeco-AMI system offers an innovative solution –  automated microscopic imaging directly within the climate chamber.

How it Works: A Peek Inside the HPPCeco-AMI

The core functionality revolves around two key aspects:

  • Microscopic Imaging: The HPPCeco-AMI utilizes high-resolution microscopic technology from Opto to capture high-quality images of your samples throughout the experiment. This eliminates the need to remove samples, minimizing disruptions and potential contamination.
  • Automated Analysis and Monitoring: Leveraging the power of Artificial Intelligence (AI), the HPPCeco-AMI goes beyond simple image capture. The system can be programmed to perform intelligent analysis on the captured images, allowing for real-time monitoring of crucial cellular or material changes within your samples. This automated analysis provides researchers with a wealth of data without the need for constant manual intervention that can affect sample integrity through sample contamination and fluctuations in temperature.

Benefits for Researchers: A Game Changer in Climate-Controlled Microscopy

The HPPCeco-AMI offers a multitude of advantages for researchers working with climate-sensitive samples:

  • Minimized Disruptions: By eliminating the need to remove samples for imaging, the HPPCeco-AMI safeguards the integrity of your experiment. This is particularly crucial for temperature and humidity sensitive cell cultures or material studies.
  • Reduced Risk of Contamination: Extracting samples for microscopic observations can introduce external contaminants, jeopardizing the sterility of your experiment. The HPPCeco-AMI's in-chamber imaging eliminates this risk, ensuring the validity of your data.
  • Enhanced Efficiency: Automated image capture and analysis free researchers from the time-consuming task of manual microscopy. This allows for more efficient use of laboratory time and resources.
  • Continuous Monitoring: The HPPCeco-AMI's ability to capture images at regular intervals enables researchers to monitor cellular or material changes over time. This provides a more comprehensive understanding of the sample's behaviour under controlled conditions.
  • Improved Data Quality: The system's AI-powered analysis capabilities can identify subtle changes in your samples that might be missed by the human eye. This leads to more objective and reliable data collection.

Applications: Unlocking the Potential of HPPCeco-AMI

The HPPCeco-AMI's versatility makes it a valuable tool across diverse scientific disciplines:

  • Cell Culture Studies: The HPPCeco-AMI allows for real-time monitoring of cell growth, morphology, and response to external stimuli within a precisely controlled environment.
  • Pharmaceutical Research: The HPPCeco-AMI is ideal for stability testing of new drugs under controlled climatic conditions. This ensures the efficacy and integrity of pharmaceutical formulations throughout their shelf life.
  • Microbial Growth: The system can be used to assess the effects of various factors such as temperature and humidity on microbial growth.
  • Material Science: Researchers can monitor material behaviour under varying temperature and humidity conditions to assess material performance and degradation.

The HPPCeco-AMI represents a significant advancement in the field of climate-controlled microscopy. By offering a non-invasive and automated solution, researchers can gain deeper insights into their samples' behavior under controlled conditions, ultimately leading to more robust and reliable scientific data.

Technical Details of the Climate Chamber

The Memmert climate chamber HPPCeco-AMI offers temperature settings from +0 °C to +70 °C and a humidity range from 10 % rh to 90 % rh making it ideally suited for stability tests in the pharmaceutical industry, e.g. ICH guideline Q1A. Further typical areas of application include shelf-life tests in the pharmaceutical, food and cosmetic sectors and quality control testing for different kinds of components.

What’s more, the HPPCeco-AMI offers active CO2 control from 0% to 20% thus expanding the range of applications to include the cultivation of living cultures such as bacteria and fungal strains in the pharmaceutical and biochemistry sectors.

Key Advantages:

  • Absolutely homogeneous distribution of temperature and humidity.
  • Reliable and fail-safe – even after years of continuous operation.
  • Always a good climate: quiet, compact, low-maintenance.

Technical Details of the Digital Microscopes

Opto digital microscopes (imaging modules) bring an unprecedented level of user-friendly and easy-to-integrate imaging performance to any production environment – from measuring machines and inspection systems to bio-imaging instruments.
Each module comes complete with its own SDK and comprehensive free image capture software, so it can be easily integrated into any existing network or system.

High-resolution, perfectly matched optical designs with latest image sensors and high-performance LEDs in a compact aluminium housing.
USB3 or GigE interface with compatibility to most image processing libraries.
Ultimate image quality, easy integration, guaranteed performance in any application.

Key Advantages:

  • Powerful imaging with simple plug-and-play functionality.
  • Enhanced image quality thanks to perfectly matched component selection.
  • Robust aluminium block design with different mounting options.
  • Includes OptoViewer and various application plug-ins.
  • Software integration tools: C/C++ OptoSDK, NI LabVIEW Toolkit, NI Vision Builder Plugin.

About Opto

Opto, based in Munich/Germany, is one of the leading manufacturers of digital microscopes for both standard and customized series production. These imaging modules are specifically designed for machine integration in medical technology and industrial applications. They provide image data that can be reproduced anytime and anywhere, making them ideal for any automation task.

Imaging modules are robust vision sensors with integrated camera, optics, lighting and electronics. Over the past 40 years, Opto has succeeded in establishing itself as an international OEM supplier focusing on microscopy and industrial image processing.

To find out more about this set up, contact support @camlab.co.uk.

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